About

1MOL Ltd. was founded in July 2022 in Sofia, Bulgaria. We are a team of professionals with strong expertise in organic synthesis, process development and chemical analysis. We aim to develop high quality commercial scientific services in the field of organic chemistry.

Our clients:  pharmaceutical companies, universities, scientific groups and scientific trade platforms worldwide.

We serve researchers in biochemistry, drug research, ecology, chemical technology, fundamental chemistry etc.

Our mission: to bring out high quality chemical support empowering researchers to make their best work.

Among our customers:

Chemical R&D

For our customers we perform custom synthesis and contract research services which include:

• Synthesis of inquired compounds
• Hit optimization, Hit-to-Lead, Lead optimization
• Development of screening libraries
• Chemical process development
• Synthesis optimization and scale-up

Our service business models include: FTE (Full Time Equivalent), FFS (Fee For Service)

Reference compounds

We synthesize on demand and sell from our stock various reference compounds of high purity (>98 % NMR and HPLC-UV):

• Bioactive small molecules (BSM)
• Enzyme inhibitors
• Drug metabolites
• Stable isotope-labeled BSM (¹³C, D, etc.)
• Environmental standards
• Persistent pollutants (PFAS, Toxaphene congeners, PCN, etc.)
• Degradation products of polutants
• Stable isotope-labeled evironmental standards (¹³C, D, etc.)

Research chemicals

We synthesize on demand and sell from our stock various compounds of different structural types:

• Heterocycles
• Peptides
• Sugars
• Ligands
• Fluorescent dyes and tagged molecules
• Caged compounds

Troubleshooting

Our services help customers solve difficult chemical problems:

• Reaction methodology optimization (catalyst, solvent, thermal regime, etc.)
• Identification of admixtures and purification of complex molecules
• Purity assessment of chemical compounds by different techniques: HPLC, GC, NMR